L-LEUCINE

Description

NDC: 53335-077-11 (capsule), 53335-076-29 (powder)

Weight: 4 Oz

L-Leucine is an essential branched-chain amino acid (BCAA) vital for protein synthesis and promoting anabolic effects, making it essential for individuals engaged in intense exercise and athletic activities. It meets the increased protein needs of athletes on calorie-restricted programs and reduces muscle catabolism in bedridden patients. L-Leucine also supports tissue repair in post-surgical patients, aiding muscle, bone, and skin recovery, while helping to stabilize blood sugar and energy levels. Research underscores its role as a key regulator of muscle protein metabolism and recovery (e.g., Norton et al. 2006).

L-Leucine is particularly beneficial for athletes, those recovering from surgery, or individuals at risk of muscle loss, offering critical support during metabolic stress. Manufactured using premium pharmaceutical-grade materials in a GMP-approved facility in the USA, L-Leucine is free of fillers, binders, or coloring agents, with no known side effects when used as directed.

Directions: Take 1-3 capsules daily or as advised by your healthcare provider. Pair with vitamins and minerals; GPD’s MVM (Multivitamin) is recommended. Powder equivalent: 1/4 level teaspoon per capsule.

Key Benefits

• Supports Muscle Growth: Promotes protein synthesis and anabolic effects.
• Aids Tissue Repair: Assists recovery in post-surgical patients.
• Stabilizes Energy Levels: Helps maintain blood sugar balance.

References

• Norton LE, et al. (2006). “Leucine regulates translation initiation of protein synthesis in skeletal muscle after exercise.” Journal of Nutrition, NIH.
• Layman DK. (2003). “Role of leucine, isoleucine, and valine in muscle metabolism.” Nutrition Reviews, NIH.
• Wolfe RR. (2017). “Branched-chain amino acids and muscle protein synthesis.” The Journal of International Society of Sports Nutrition, NIH.
• Matthews DE. (2005). “Observations of branched-chain amino acid administration in humans.” The Journal of Nutrition, NIH.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a doctor or medical professional before use, especially if you have underlying health conditions or are taking other medications.

Additional Information The following points provide insight into L-Leucine’s plasma levels and their association with various health conditions, reflecting its role in metabolism:

• Normal Range: 80-180 micromol/L (approximate clinical range).
• Conditions Associated with Low Levels:
  • Malnutrition (due to inadequate protein intake)
  • Prolonged fasting or starvation (increased catabolism)
  • Muscle-wasting diseases (e.g., cachexia)
• Conditions Associated with High Levels:
  • Excessive supplementation (from overdosage or dietary excess)
  • Maple syrup urine disease (genetic disorder affecting BCAA metabolism)
  • Post-exercise states (temporary elevation from protein breakdown)

Notes: L-Leucine is an essential branched-chain amino acid critical for protein synthesis, muscle anabolism, and tissue repair, particularly under exercise or catabolic stress. It helps stabilize blood sugar and energy levels, with benefits for athletes and recovering patients. Low levels may indicate nutritional deficits or muscle loss, while high levels can result from supplementation or metabolic disorders. These associations are correlative and require further research for causal confirmation. For more technical information, please click here. Consult a doctor or medical professional before use, especially if you have underlying health conditions or are taking other medications.