L-GLYCINE

Description

NDC: 53335-071-14 (capsule), 53335-070-29 (powder)

Weight: 4 Oz

L-Glycine is a non-essential amino acid that plays a multifaceted role in human physiology. It promotes gluconeogenesis, supports the formation of collagen found in skin and connective tissues, and aids in the synthesis of creatine to prevent muscle tissue degeneration, potentially benefiting conditions like muscular dystrophy. As an inhibitory neurotransmitter, L-Glycine supports central nervous system function and may influence epilepsy management. It participates in the synthesis of purines, porphyrins, and glyoxylic acid, contributes to prostate health, and is involved in bile acid metabolism and gastrointestinal function. Research also suggests its potential in reducing liver tumor growth and supporting neurological health (e.g., Rose et al. 1999).

L-Glycine is particularly beneficial for individuals seeking to enhance muscle integrity, support neurological balance, or improve metabolic detoxification under stress. Manufactured using premium pharmaceutical-grade materials in a GMP-approved facility in the USA, L-Glycine is free of fillers, binders, or coloring agents, with no known side effects when used as directed.

Directions: Take 1-3 capsules daily or as advised by your healthcare provider. Pair with vitamins and minerals; GPD’s MVM (Multivitamin) is recommended. Powder equivalent: 1/4 level teaspoon per capsule.

Key Benefits

• Supports Muscle Health: Aids collagen and creatine synthesis.
• Enhances Neurological Function: Acts as an inhibitory neurotransmitter.
• Promotes Detoxification: Supports bile acid and metabolic processes.

References

• Rose ML, et al. (1999). “Dietary glycine prevents liver tumors caused by WY-14,643.” Carcinogenesis, NIH.
• Gusev EI, et al. (2000). “Neuroprotective effects of glycine in acute ischaemic stroke.” Cerebrovascular Diseases, NIH.
• Kasai K, et al. (1978). “Stimulatory effect of glycine on human growth hormone secretion.” Metabolism, NIH.
• Banay-Schwartz M, et al. (1993). “Heterogeneous distribution of amino acids in brain areas.” Neurochemical Research, NIH.
• Di Pasquale M. (1997). Amino Acids and Proteins for the Athlete: The Anabolic Edge. CRC Press.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult a doctor or medical professional before use, especially if you have underlying health conditions or are taking other medications.

Additional Information The following points provide insight into L-Glycine’s plasma levels and their association with various health conditions, reflecting its role in metabolism:

• Normal Range: 150-500 micromol/L (approximate clinical range).
• Conditions Associated with Low Levels:
  • Malnutrition (due to reduced amino acid intake)
  • Chronic liver disease (impaired glycine metabolism)
  • Neurological disorders (e.g., epilepsy, affecting neurotransmitter balance)
• Conditions Associated with High Levels:
  • Excessive supplementation (from overdosage or dietary excess)
  • Renal failure (reduced excretion of glycine)
  • Metabolic acidosis (increased glycine as a buffer)

Notes: L-Glycine is a non-essential amino acid that supports gluconeogenesis, collagen formation, and creatine synthesis, while functioning as an inhibitory neurotransmitter. It aids in detoxification via bile acid metabolism and may reduce tumor growth or support neurological health. Low levels may indicate nutritional or liver deficits, while high levels can result from supplementation or renal impairment. These associations are correlative and require further research for causal confirmation. For more technical information, please click here. Consult a doctor or medical professional before use, especially if you have underlying health conditions or are taking other medications.